Neuronal dysfunction caused by FUSR521G promotes ALS-associated phenotypes that are attenuated by NF-κB inhibition.

"Declarations Competing interestsThe authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Competing interests The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest."

"Funding This work was supported by Brain Canada Future Leader’s Award (to C.F.S), ALS Canada–Brain Canada Career Transition Award and ALS Canada Bridge Funding (to C.F.S), Natural Sciences and Engineering Research Council of Canada Grants RGPIN-2020-06376 and DGECR-2020-00060 (to C.F.S), RGPIN-2018-06227 and DGECR-2018-00093 (to P.A.D) and Fonds de Recherche du Québec Santé Junior 1 (to C.F.S and P.A.D.)."