TIGIT reverses IFN-α-promoted Th1-like Tregs via in-sequence effects dependent on STAT4.

"Declarations Ethics approval and consent to participateThe study was conducted in accordance with the fundamental principles and regulations of the national and ethical requirements. The local ethics committee of the First Hospital of China Medical University ([2019] No. 2019–8-2) has approved the research protocol and written informed consent was obtained from the subjects. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was supported by the National Natural Science Foundation of China (grant numbers 81901658, 82102266) and Liaoning Province Natural Science Foundation (2022-BS-134)."