Molecular and functional profiling of chemotolerant cells unveils nucleoside metabolism-dependent vulnerabilities in medulloblastoma.

"expression data were deposited into the gene expression omnibus (geo) database under series accession number gse220543 and are accessible without restrictions.; availability of data and materials the gene expression datasets generated during the current study are available in the geo repository under series accession number gse220543 and are accessible without restrictions. availability of data and materials the gene expression datasets generated during the current study are available in the geo repository under series accession number gse220543"

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding Open access funding provided by Università degli Studi di Padova. This work was supported by funds from Istituto di Ricerca Pediatrica Città della Speranza (Project No. IRP18/06), the Rally Foundation for Childhood Cancer Research (#20IN28 and #21IC16), Cassa di Risparmio di Padova e Rovigo (CARIPARO) Foundation (Project no. 17/07_1 FCR to SB and Project No. 20/16 FCR to LP), Fondazione Just Italia (“Più forti di tutto”), and Italian Association for Cancer Research (AIRC) (IG #23109) (to GV). AC (#4420 and #4820) and ER (#3628) were supported by fellowships from the Umberto Veronesi Foundation. EM was supported by fellowships from AIRC (ID 24185). Funding sources were not involved in any process of study design, data interpretation, or manuscript writing and submission."