Expression quantitative trait loci analysis in rheumatoid arthritis identifies tissue specific variants associated with severity and outcome.

"the rna-seq data have been deposited in arrayexpress under accession code e-mtab-6141.; the rna-seq data have been deposited in arrayexpress under accession code e-mtab-6141. gc =1 04 in blood) cis -eqtl manhattan plots ( figure 1c ) highlight the most significant genes in synovium (top) and blood (bottom) where the dashed lines represent genome-wide significance (fdr<=0 01) 10 1136/ard-2023-224540 supp2 supplementary data 10 1136/ard-2023-224540 supp1 supplementary data figure 1 cis- eqtl for blood and synovium in early rheumatoid arthritis cis -eqtl analysis was performed on 85 synovial and 51 blood samples using matrixeqtl (a). data availability statement data are available in a public open access repository. the rna-seq data have been deposited in arrayexpress under accession code e-mtab-6141"

"Competing interests: None declared."

"Funding: This work was supported by the MRC/Arthritis Research UK award: Maximising Therapeutic Utility in RA (MATURA) (grant MR-K015346) and MRC TRACT-RA (MR/V012509/1). The Pathobiology of Early Arthritis Cohort (PEAC) was supported by funding from the MRC (grant number G0800648)."