Irisin suppresses pancreatic β cell pyroptosis in T2DM by inhibiting the NLRP3-GSDMD pathway and activating the Nrf2-TrX/TXNIP signaling axis.
Journal Information
Full Title: Diabetol Metab Syndr
Abbreviation: Diabetol Metab Syndr
Country: Unknown
Publisher: Unknown
Language: N/A
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Subject Category: Endocrinology & Metabolism
Available in Europe PMC: Yes
Available in PMC: Yes
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"Declarations Ethics approval and consent to participateAnimal experiments were conducted under protocols approved by the First People’s Hospital of Yunnan Province, the Affiliated Hospital of Kunming University of Science and Technology. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."
"Funding This study was supported by Joint Special Funds for the Yunnan Provincial Science and Technology Department-Kunming Medical University [Grant Numbers: 202001AY070001–293, 202101AY070001–256], and Yunnan health training project of high level talents [Grant Number: H-2019023]."
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Last Updated: Aug 05, 2025