Assessment of hypoxia and oxidative-related changes in a lung-derived brain metastasis model by [⁶⁴Cu][Cu(ATSM)] PET and proteomic studies.

"Declarations Ethics approval and consent to participateAll animal investigations were performed under the current European directive (2010/63/EU) and are presented following the ARRIVE guidelines. This study was undertaken in the housing and laboratory (F14118001; G14 118 001) and with the permission of the regional committee on animal ethics (C2EA-54 CENOMEXA, project APAFIS#8941). Consent for publicationInformed consent was obtained from all individual participants included in the study. Competing interestThe authors declare that they have no competing interests. Competing interest The authors declare that they have no competing interests."

"Funding This research was funded by the French National Agency for Research “Investissements d’Avenir” n° ANR-11-LABEX-0018-01, the Région Normandie (RIN HYPOTHERA, RIN HYP-IRON2), the Centre National de la Recherche Scientifique (CNRS), the Université Caen-Normandie, J.F. was supported by the ANR, CNRS and the Région Normandie. C.H. was supported by the Région Normandie."