A global view of aging and Alzheimer's pathogenesis-associated cell population dynamics and molecular signatures in human and mouse brains.

"code availability customized computational scripts of processing easysci data were deposited in zenodo 109 (10 5281/zenodo 8395492) and github ( https://github com/junyuecaolab/easysci ). code availability customized computational scripts of processing easysci data were deposited in zenodo 109 (10 5281/zenodo 8395492) and github ( https://github com/junyuecaolab/easysci )."

"code availability customized computational scripts of processing easysci data were deposited in zenodo 109 (10 5281/zenodo 8395492) and github ( https://github com/junyuecaolab/easysci )."

"Competing interests J.C., W.Z., A.S. and J.L. are inventors on pending patent applications related to EasySci-RNA-seq. The other authors declare no competing interests."

"We thank all members of the Cao lab for helpful discussions and feedback. We thank J. Shendure (University of Washington) for insightful feedback on this work. We also thank members of the Rockefeller University Genomics Resource Center (SCR_020986), High-Performance Computing Resource Center and Comparative Bioscience Center for their exceptional assistance with library sequencing and animal maintenance. This work was funded by grants from the National Institutes of Health (DP2HG012522, R01AG076932 and RM1HG011014 to J.C.; P30AG072946 and P01AG078116 to P.T.N.; and R01AG072758 to L.G.) and the Sagol Network GerOmic Award (J.C.). This work is partly supported by the Pershing Square Foundation, Bill Ackman and Neri Oxman."