Targeting integrin α5 in fibroblasts potentiates colorectal cancer response to PD-L1 blockade by affecting extracellular-matrix deposition.

Authors:
Lu L; Gao Y; Huang D; Liu H; Yin D and 12 more

Journal:
J Immunother Cancer

Publication Year: 2023

DOI:
10.1136/jitc-2023-007447

PMCID:
PMC10693881

PMID:
38040421

Journal Information

Full Title: J Immunother Cancer

Abbreviation: J Immunother Cancer

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Therapeutics

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Competing interests: None declared."

Evidence found in paper:

"Funding: This work was supported by the Fundamental Research Funds for the Central Universities (22120220644), the National Natural Science Foundation of China (81700478, 82273366 and 82072634), Science and Technology Commission of Shanghai (20ZR1442800) and Clinical research plan of SHDC (No. SHDC2020CR2069B and No. SHDC2020CR5006–002)."

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Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025