Astrocyte-specific knockout of YKL-40/Chi3l1 reduces Aβ burden and restores memory functions in 5xFAD mice.

Authors:
Zeng X; Cheung SKK; Shi M; Or PMY; Li Z and 7 more

Journal:
J Neuroinflammation

Publication Year: 2023

DOI:
10.1186/s12974-023-02970-z

PMCID:
PMC10693711

PMID:
38042775

Journal Information

Full Title: J Neuroinflammation

Abbreviation: J Neuroinflammation

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Neurology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Declarations Ethics approval and consent to participateAll animal works were approved by the Hong Kong Department of Health and conducted in accordance with the Animal Experimentations and Ethics Committee of the Chinese University of Hong Kong (No.18-104-GRF) and by Animal Ethics Committee of Weifang Medical University (No. 2019SDL055). Consent for publicationNot applicable. Competing interestsAll authors do not have any competing interests to declare. Competing interests All authors do not have any competing interests to declare."

Evidence found in paper:

"Funding This study was supported by a General Research Fund grant (#14123718) to AMC from the University Grants Committee of Hong Kong, and a General Program Grant (ZR2020MH146) to YW from the Shandong Provincial Natural Science Foundation."

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Open Access
Paper is freely available to read
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Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025