Fibrinogen Early In Severe Trauma studY (FEISTY): results from an Australian multicentre randomised controlled pilot trial.

"Competing interests James Winearls has received educational, travel and research support from Werfen, Haemonetics and CSL Behring. Shane George has received research support for FEISTY Junior from Werfen, Haemonetics and CSL Behring."

"The program of trauma research that we undertake is supported by grants from the Emergency Medicine Foundation (grant EMPJ357R25-2016), National Blood Authority (grant 127) and Gold Coast University Hospital (grant 150-16.6.16). This trial was supported by Werfen, Haemonetics and CSL Behring in terms of materials only. There was no industry input into trial design, data collection, data analysis or dissemination of results. Funding was managed by the coordinating site – Gold Coast University Hospital and University of Queensland."

"FEISTY was an investigator-initiated, multicentre, randomised controlled, pilot trial comparing FC with Cryo for fibrinogen replacement in traumatic haemorrhage. It was conducted in four major trauma centres in Queensland, Australia, between December 2016 and September 2017. The trial was prospectively registered on ClinicalTrials.gov (NCT02745041). A full trial protocol has previously been published."