Cryo-EM structures of Aβ40 filaments from the leptomeninges of individuals with Alzheimer's disease and cerebral amyloid angiopathy.

"fitting our model into the 4 4 a map (emd-10204) [ ] and comparing it with the deposited model (pdb:6shs) shows that our model is as good a description of the 4 4 a map as the deposited model (fig 5 e).; availability of data and materials cryo-em maps have been deposited in the electron microscopy data bank (emdb) with the accession numbers emd-18508 and emd-18509.; corresponding refined atomic models have been deposited in the protein data bank (pdb) under accession numbers pdb:8qn6 and pdb:8qn7. availability of data and materials cryo-em maps have been deposited in the electron microscopy data bank (emdb) with the accession numbers emd-18508"

"Declarations Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This work was funded by the Medical Research Council, as part of UK Research and Innovation (MC-U105184291 to MG and MC-UP-A025-1013 to SHWS). It was also supported by the US National Institutes of Health (RF1 NS110437 and P30 AG072976 to BG)."