Ultrasound-guided dexmedetomidine combination with modified high fascia iliaca compartment block for arthroscopic knee surgery: what is the optimal dose of dexmedetomidine?

"Declarations Ethics approval and consent to participateStudy approval was obtained from the Institutional Review Board of Ethics Committee of Affiliated Hospital of Nantong University (registration number 2022-K023) on 20/04/2022 and the PODCAST trial is registered with clinicaltrials.gov, number NCT05533970 on 09/09/2022. Patients and their family members informed the treatment and signed a consent form. The trial was conducted in accordance with the Declaration of Helsinki. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This study was supported by grants from the Social Development Foundation of Nantong City (MSZ2022036)."

"This prospective study included a total of 120 patients who were scheduled for elective TKA and were enrolled at the Affiliated Hospital of Nantong University from October 2022 to December 2022. Study approval was obtained from the Institutional Review Board of Ethics Committee of Affiliated Hospital of Nantong University (number: 2022-K023) and the PODCAST trial is registered with clinicaltrials.gov, number NCT05533970 on 09/09/2022. Patients and their family members were informed about the treatment and signed a consent form. The trial was conducted in accordance with the Declaration of Helsinki. Declarations: Ethics approval and consent to participateStudy approval was obtained from the Institutional Review Board of Ethics Committee of Affiliated Hospital of Nantong University (registration number 2022-K023) on 20/04/2022 and the PODCAST trial is registered with clinicaltrials.gov, number NCT05533970 on 09/09/2022. Patients and their family members informed the treatment and signed a consent form. The trial was conducted in accordance with the Declaration of Helsinki.: Consent for publicationNot applicable.: Competing interestsThe authors declare no competing interests. Ethics approval and consent to participate: Study approval was obtained from the Institutional Review Board of Ethics Committee of Affiliated Hospital of Nantong University (registration number 2022-K023) on 20/04/2022 and the PODCAST trial is registered with clinicaltrials.gov, number NCT05533970 on 09/09/2022. Patients and their family members informed the treatment and signed a consent form. The trial was conducted in accordance with the Declaration of Helsinki."