Quercetin is a Potential Therapy for Rheumatoid Arthritis via Targeting Caspase-8 Through Ferroptosis and Pyroptosis.

"two datasets for ra were included gse55235 and gse77298 which were screened using the national center for biotechnology information (ncbi) gene expression omnibus (geo) ( https://www ncbi nlm nih gov/geo/ ) as shown in table 1 . the flowchart of this study is shown in figure 1 and all raw data has been uploaded to github which is https ( https://github com/zheng5862/zheng5862 git ).; all the raw data is contained in supplementary material and uploaded to github which is https ( https://github com/zheng5862/zheng5862 git ). data sharing statement publicly available datasets (gse55235"

"we used the comparative toxicogenomics database (ctd http://ctdbase org/ ) the tcmsp database ( https://old tcmsp-e com/tcmsp php ) the genecards database and the chembl database ( https://www ebi ac uk/chembl/ ) to find potentially relevant genes for quercetin ( supplementary material has been uploaded to github).; the flowchart of this study is shown in figure 1 and all raw data has been uploaded to github which is https ( https://github com/zheng5862/zheng5862 git ).; all the raw data is contained in supplementary material and uploaded to github which is https ( https://github com/zheng5862/zheng5862 git ). we used the comparative toxicogenomics database (ctd http://ctdbase org/ ) the tcmsp database ( https://old tcmsp-e com/tcmsp php ) the genecards database and the chembl database ( https://www ebi ac uk/chembl/ ) to find potentially relevant genes for quercetin ( supplementary material has been uploaded to github).; all the raw data is contained in supplementary material and uploaded to github which is https ( https://github com/zheng5862/zheng5862 git )."

"Disclosure The authors declare that the research was conducted without commercial or financial relationships construed as a potential conflict of interest."

"The Natural Science Foundation of Fujian Province (No. 2020J01947, No. 2021J02035) and Fujian Provincial Health Technology Project (No. 2020CXA039, No. 2021CXA019) supported the study."