An Ancestral Major Histocompatibility Complex Organization in Cartilaginous Fish: Reconstructing MHC Origin and Evolution.

"for this purpose only fully annotated high-contiguity chromosome-level wga of representatives from the 2 sister lineages of elasmobranchs available on ncbi in december 2021 were included namely for sharks: white shark c carcharias scarcar2 (gca_017639515 1 released in may 2021) and catshark scyliorhinus canicula sscycan1 1 (genbank gca_902713625 1 released in january 2021); and for rays: thorny skate amblyraja radiata (gca_010909765 2 released in april 2021)."

"Conflict of interest statement. None declared."

"This work was supported by Portuguese funds through the Portuguese Foundation for Science and Technology via a DL57/2016 contract (to A.V.); M.F.F. and Y.O. are supported by National Institutes of Health Grants R01AI140326 and R01AI170844; A.M.M. was supported by project NORTE-01-0246-FEDER-000063, Norte Portugal Regional Operational Programme (NORTE2020), under the PORTUGAL 2020 Partnership Agreement, through the European Regional Development Fund (ERDF). This work is also financed by FEDER Funds through the Operational Competitiveness Factors Program COMPETE and by national funds through the Foundation for Science and Technology within the scope of Project PTDC/ASP-PES/28053/2017, which supported also AG and FN. Work supported by the European Union’s Horizon 2020 Research and Innovation Programme under the Grant Agreement Number 857251."