Pathological progress and remission strategies of osteoarthritic lesions caused by long-term joint immobilization.

"Declarations Ethics approval and consent to participateThis clinical retrospective study was approved by the Ethics Committee of Linyi People’s Hospital. The animal protocols of this study were approved by the Institutional Animal Care and Use Committee of the Southern University of Science and Technology. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

"Funding This work was supported, in part, by the National Natural Science Foundation of China Grants (82250710175, 82261160395, 82230081, 81991513, 82172375), the Shenzhen Fundamental Research Program (JCYJ20220818100617036), the Guangdong Provincial Science and Technology Innovation Council Grant (2017B030301018), the Shenzhen Key Laboratory of Cell Microenvironment Grant (ZDSYS20140509142721429), the China Postdoctoral Science Foundation (2022M711499), the Youth Project of Natural Science Foundation of Shandong Province (ZR2021QH230), and the Joint Foundation Project of Natural Science Foundation of Shandong Province (ZR2022LZY002)."