Application of SHAP values for inferring the optimal functional form of covariates in pharmacokinetic modeling.

Authors:
Janssen A; Hoogendoorn M; Cnossen MH; Mathôt RAA; OPTI‐CLOT Study Group and SYMPHONY Consortium.

Journal:
CPT Pharmacometrics Syst Pharmacol

Publication Year: 2022

DOI:
10.1002/psp4.12828

PMCID:
PMC9381890

PMID:
38100100

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Journal Information

Journal Title: CPT Pharmacometrics Syst Pharmacol

Detailed journal information not available.

Publication Details

Subject Category: Pharmacology & Pharmacy

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Data Sharing
Evidence found in paper:

"all model code including implementation instructions will be made available at https://github com/janssena/pkshap at the time of publication."

Evidence found in paper:

"CONFLICT OF INTEREST The authors declared no competing interests for this work."

Evidence found in paper:

"Funding information"

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Open Access
Paper is freely available to read
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Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025