PRRG4 regulates mitochondrial function and promotes migratory behaviors of breast cancer cells through the Src-STAT3-POLG axis.

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interest. Competing interests The authors declare that they have no competing interest."

"Funding This study was supported by Natural Science Foundation of Zhejiang Province (LZ23H160001) and National Natural Science Foundation of China (81972463) grants to HG, Natural Science Foundation of Zhejiang Province grants (LQ23H160012, LTGY23H080005) to JC and LH, National Natural Science Foundation of China grant (82272702) to GW, Wenzhou Sciences and Technology Bureau of China (Y2020416), and Medical and Health Science and Technology Plan Project of Zhejiang Province, China (2021KY1083) to ML, and in part supported by the Key Discipline of Zhejiang Province in Medical Technology (First Class, Category A) and Wenzhou Key Laboratory of Cancer Pathogenesis and Translation. "