Translational profiling identifies sex-specific metabolic and epigenetic reprogramming of cortical microglia/macrophages in APPPS1-21 mice with an antibiotic-perturbed-microbiome.

"availability of data and materials all mass spectrometry data (raw files and maxquant search result files) are publicly available on proteomexchange repository ( www proteomexchange org ) with the identifier pxd035094."

"Declarations Ethics approval and consent to participateAll experimental procedures involving animals were performed in accordance with the approved Animal Care and Use Protocols by the Institutional Animal Care and Use Committee at the University of Chicago (IACUC). Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding This study was supported by the Cure Alzheimer’s Fund, Open Philanthropy Project, Good Ventures Foundation, and Luminescence Foundation (to S.S. Sisodia)."