Simulation of neuroplasticity in a CNN-based <i>in-silico</i> model of neurodegeneration of the visual system.

"Conflict of interest The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. The author(s) declared that they were an editorial board member of Frontiers, at the time of submission. This had no impact on the peer review process and the final decision."

"The author(s) declare financial support was received for the research, authorship, and/or publication of this article. This work was supported by the Canada Research Chairs program, the River Fund at Calgary Foundation, Natural Sciences and Engineering Research Council of Canada (NSERC), Alberta Innovates – Data Enabled Technologies, and from the NSERC – Hotchkiss Brain Institute Brain CREATE program. The funding agencies had no role in the study design, collection, analysis and interpretation of data, nor preparation, review or approval of the manuscript. KF was supported by Deutsche Forschungsgemeinschaft (DFG) grant SFB 936/A1, FH by DFG grant TRR 169/A1, and CH by DFG grants SFB 936/A1, SFB 936/Z3; TRR 169/A2 and SFB 1461/A4."