Oral Metformin Inhibits Choroidal Neovascularization by Modulating the Gut-Retina Axis.

"Disclosure: J.Y. Zhang, None; J. Xiao, None; B. Xie, None; H. Barba, None; M. Boachie-Mensah, None; R.N. Shah, None; U. Nadeem, None; M. Spedale, None; N. Dylla, None; H. Lin, None; A.M. Sidebottom, None; M. D'Souza, None; B. Theriault, None; D. Sulakhe, None; E.B. Chang, None; D. Skondra, None"

"Supported by Genentech AMD Research Fellowship “Common antidiabetic drug metformin prevents AMD by reshaping the gut microbiome” (D. Skondra), Institute for Translational Medicine (D. Skondra), BrightFocus Foundation “Role of high fat diet and gut microbiome in macular degeneration” (D. Skondra, M2018042), NIDDK P30 (E.B.C., DK42086), The University of Chicago Women's Board (D. Skondra), FORE-I Foundation (D. Skondra), and the Illinois Society for the Prevention of Blindness (D. Skondra, FP067271-01-PR)."