LncRNA AGAP2 antisense RNA 1 stabilized by insulin-like growth factor 2 mRNA binding protein 3 promotes macrophage M2 polarization in clear cell renal cell carcinoma through regulation of the microRNA-9-5p/THBS2/PI3K-Akt pathway.

"Declarations Ethics approval and consent to participateAll experiments were conducted according to the ethical guidelines of the Ethics Committee of Mianyang Central Hospital and strictly followed the "Declaration of Helsinki". All patients signed written informed consent. The Animal Ethics Committee of Mianyang Central Hospital has approved the experimental procedure and animal use protocol. Consent for publicationNot applicable. Competing interestsAll authors declare no financial competing interests.All authors declare no non-financial competing interests. Competing interests All authors declare no financial competing interests. All authors declare no non-financial competing interests."

"Funding This work was supported by the Science and Technology Department of Sichuan Province (2019YJ0701, and 2021YJ0239)."