Effect of perioperative branched chain amino acids supplementation in liver cancer patients undergoing surgical intervention: A systematic review.

"Conflict-of-interest statement: The authors deny any conflict of interest."

"This systematic review was performed in accordance with the Preferred Reporting Items of Systematic Reviews and Meta-Analyses (PRISMA) guidelines[]. This review is part of a systematic review protocol registered on PROSPERO (CRD42022341658). Search of five databases (PubMed, Embase, Cochrane Library, Scopus, and Web of Science) was conducted on July 6, 2022 for articles published since inception up to 6 July 2022. Keywords related to the terms (“BCAA” or “Branched-chain amino acid” or “Leu” or “Val” or “Ile” or “amino acid”), [(“liver” or “hepatic” or “hepatocellular”) and (“carcinoma” or “cancer” or “malignancy” or “tumour” or “neoplasm”)], (“resection” or “surgery” or “preoperative” or “perioperative” or “postoperative” or “hepatectomy” or “liver transplantation”) were used in literature search. The full search strategy is available in Supplementary Table 1."