CNP blocks mitochondrial depolarization and inhibits SARS-CoV-2 replication in vitro and in vivo.

Journal Information

Full Title: PLoS Pathog

Abbreviation: PLoS Pathog

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Microbiology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Evidence found in paper:

"plos publication stage vor-update-to-uncorrected-proof publication update 2024-01-04 data availability all data for this manuscript is available at the center for open science at https://osf io/f6db3/ .; outbreaks covid-19 data availability all data for this manuscript is available at the center for open science at https://osf io/f6db3/ . data availability all data for this manuscript is available at the center for open science at https://osf"

Code Sharing
Evidence found in paper:

"I have read the journal’s policy and the authors of this manuscript have the following competing interests: M.B.F. is on the scientific advisory board of Aikido Pharma and has collaborative research agreements with Novavax, AstraZeneca, Regeneron, and Irazu Bio. These do not have any effect on the planning or interpretations of the work presented in this manuscript."

Evidence found in paper:

"This work is partially funded by NIH R01 AI148166 (to MBF). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025