Competing endogenous RNA network analysis of Turner syndrome patient-specific iPSC-derived cardiomyocytes reveals dysregulation of autosomal heart development genes by altered dosages of X-inactivation escaping non-coding RNAs.

"the microarray data were deposited in the gene expression omnibus (geo) database under the accession no gse239758.; availability of data and materials the microarray data of this study are available in the gene expression omnibus (geo) database under the accession no gse239758. availability of data and materials the microarray data of this study are available in the gene expression omnibus (geo) database under the accession no gse239758"

"Declarations Ethics approval and consent to participateThis study was performed in accordance with the Declaration of Helsinki and approved by the Ethics Committee of The Third Affiliated Hospital of Guangzhou Medical University with the Ethics Review Report #2017/058 for the research project titled “Screening of circRNAs associated with fetal development of Turner syndrome and research on their functional mechanisms” on 19 October 2017. Informed consents were obtained from the donors of PBMCs. Consent for publicationNot applicable. Competing interestsThe authors declared no competing interests. Competing interests The authors declared no competing interests."

"Funding This study was supported by the National Natural Science Foundation of China (82002774), Guangdong Basic and Applied Basic Research Foundation (2020A1515010065), Guangzhou City Science and Technology Project (202201020208), Guangzhou City Science, Technology and Innovation Commission (202002030077), Guangdong Province Outstanding Youth Medical Talent Program (110217110) and Lin He's Academician Workstation of New Medicine and Clinical Translation at The Third Affiliated Hospital of Guangzhou Medical University (2021HLKY05). The funding bodies played no role in design of the study and collection, analysis and interpretation of the data and in writing the manuscript."