Safety and immunogenicity of a synthetic nanoparticle-based, T cell priming peptide vaccine against dengue in healthy adults in Switzerland: a double-blind, randomized, vehicle-controlled, phase 1 study.

Journal Information

Full Title: EBioMedicine

Abbreviation: EBioMedicine

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics, Medical

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Data Sharing
Code Sharing
Evidence found in paper:

"Declaration of interests All authors and the PV CRO Qvigilance declare no competing interests."

Evidence found in paper:

"This work was sponsored and funded by Emergex Vaccines Holding Limited. We thank the sponsor (Athanasios Papadopoulos, Lorraine Mumtaz, Thomas Rademacher, Firdos Sayed, MaiLee Tansley) for their support in the different steps of the trial and Qvigilance for the safety data management."

Evidence found in paper:

"This study was approved by the local ethics committee (Commission cantonale (Vaud) d'éthique de la recherche sur l'être humain, 2020-02258) and by Swiss regulatory authorities (Swissmedic, 2021DR1042). All participants provided written informed consent. This study is registered at ClinicalTrials.gov, NCT04935801."

Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025