Benchmarking splice variant prediction algorithms using massively parallel splicing assays.

"availability of data and materials datasets scored by all the algorithms are available as supplementary tables and the jupyter notebooks and source data needed to reproduce the scoring and plots are posted at github [ 116 ] and archived at zenodo [ 117 ]. availability of data and materials datasets scored by all the algorithms are available as supplementary tables and the jupyter notebooks and source data needed to reproduce the scoring and plots are posted at github [ 116 ] and archived at zenodo [ 117 ]. we tested for significance as described by braun et al (heading "significant mutation effects and synergistic interactions") using per-replicate variant scores from supplementary data 3 (sheets "hek293t rep1" "hek293t rep2" "hek293t rep3")."

"availability of data and materials datasets scored by all the algorithms are available as supplementary tables and the jupyter notebooks and source data needed to reproduce the scoring and plots are posted at github [ 116 ] and archived at zenodo [ 117 ]. availability of data and materials datasets scored by all the algorithms are available as supplementary tables and the jupyter notebooks and source data needed to reproduce the scoring and plots are posted at github [ 116 ] and archived at zenodo [ 117 ]."

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationNot applicable. Competing interestsJ.O.K. serves as a scientific advisor to MyOme, Inc. The authors declare that there are no further competing interests. Competing interests J.O.K. serves as a scientific advisor to MyOme, Inc. The authors declare that there are no further competing interests."

"Funding This work was supported by the National Institute of General Medical Sciences (R01GM129123 to J.O.K.)."