Comparative analysis of cysteine proteases reveals gene family evolution of the group 1 allergens in astigmatic mites.

"these findings shed light on the evolution of the cysteine protease gene family and provided insights into the development of component-resolved diagnosis (crd) in mite allergies2 2 1 the genome and transcriptome data of d farinae d pteronyssinus blomia tropicalis and tyrophagus putrescentiae have been reported in our previous study and deposited in the ncbi database (bioproject accession: prjna174061 prjna388362 prjna702011 prjna706095 respectively). data availability statement the genome and transcriptome sequencing data of the six astigmatic mites were available on the ncbi database (bioproject accession: prjna174061"

"CONFLICT OF INTEREST STATEMENT We have no conflict of interest to disclose."

"This work was made possible by grants: General Research Fund from Research Grants Council of Hong Kong (Reference numbers: 464710, 475113, 14119219, 14119420, 14175617), Health and Medical Research Fund from Food and Health Bureau of Hong Kong (Reference numbers: 06171016, 07181266), Continuation project of Joint Research Fund for Overseas Chinese Scholars and Scholars in Hong Kong and Macao Young Scholars (Reference number: 31729002), the National Natural Science Foundation of China (Reference numbers: 81971514, 82073950), Shenzhen Science and Technology Plan Project (Reference number: KQTD20170331145453160, GJHZ20190822095605512, SGDX20201103095609027)."