Inducible caspase 9-mediated suicide gene therapy using AAV6 vectors in a murine model of breast cancer.

"Declaration of interests S.P., V.S., N.K., and G.R.J. have applied for patents based on AAV, and some of these have been licensed to commercial entities."

"We thank Central Experimental Animal Facility, IIT Kanpur, for housing the animals and providing the microtome and cryostat facilities for tissue sectioning; Live Cell Imaging Lab, ACMS, IIT Kanpur, for assistance during confocal imaging; Dr. Saraswat’s Pathology, Kanpur for performing paraffin embedding and H&E staining; Mr. Mohankumar B. Senthilkumar for helping with the IHC experiments. We thank Dr. Dipak Datta, Central Drug Research Institute, Lucknow, India, for providing the 4T1 cells and guidance for the generation of the animal model. This research work has been supported by the intramural fund from 10.13039/501100011067IIT Kanpur. S.P. and V.S. received study fellowships from the 10.13039/501100001410Human Resource Development Group, Council of Scientific & Industrial Research and the 10.13039/501100004541Ministry of Human Resource Development, Government of India, respectively."