circMORC3-encoded novel protein negatively regulates antiviral immunity through synergizing with host gene MORC3.

Publication Year: 2023

DOI:
10.1371/journal.ppat.1011894

PMCID:
PMC10775979

PMID:
38150467

Journal Information

Full Title: PLoS Pathog

Abbreviation: PLoS Pathog

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Microbiology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"a value of p < 0 05 was considered significant s1 data (xlsx) click here for additional data file s1 table (docx) click here for additional data file s1 fig (a) the relative copy numbers of circmorc3 and morc3 in liver samples after scrv infection were detected by absolute quantitative pcr actin is control gene (b) the relative copy numbers of circmorc3 and linear morc3 in msbc cells measured by absolute quantitative pcr after scrv infection actin is control gene (c) computational analysis was used to identify the stem-loop like structure of precursor in circmorc3 (pdf) click here for additional data file s2 fig (a) sanger sequencing validation of circmorc3 flag-circmorc3 and flag-circmorc3-atg-mut overexpression plasmid capable of producing circular circmorc3 (b) qrt-pcr detection of the efficiency of circmorc3 flag-circmorc3 and flag-circmorc3-atg-mut overexpression plasmids in producing circmorc3 (pdf) click here for additional data file. xlsx) click here for additional data file s1"

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"The authors have declared that no competing interests exist."

Evidence found in paper:

"This study was supported by the National Natural Science Foundation of China (31822057, www.nsfc.gov.cn) to TX. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."

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Last Updated: Aug 05, 2025