Process Evaluation of a Double-Blind Randomized Controlled Trial to Assess the Efficacy and Safety of a Quadruple Ultra-Low-Dose Treatment for Hypertension Within a Federally Qualified Health Center Network (QUARTET USA).

"Disclosures Dr Huffman has received travel support from the American Heart Association and World Heart Federation and consulting fees from PwC Switzerland for activities outside this research. Dr Huffman has an appointment at The George Institute for Global Health, which has a patent, a license, and has received investment funding with intent to commercialize fixed‐dose combination therapy through its social enterprise business, George Medicines. Dr Huffman has pending patents for heart failure polypills. The remaining authors have no disclosures to report."

"Sources of Funding This work was supported by the National Institutes of Health, Lung, and Blood Institute (R33HL139852), National Center for Advancing Translational Sciences (UL1TR001422), and Northwestern University Feinberg School of Medicine. N.R.K. was supported by K24 HL155897."

"Registration: URL: https://www.clinicaltrials.gov; Unique identifier: NCT03640312."