TRIM26 alleviates fatal immunopathology by regulating inflammatory neutrophil infiltration during Candida infection.

Authors:
Zhao G; Li Y; Chen T; Liu F; Zheng Y and 5 more

Journal:
PLoS Pathog

Publication Year: 2024

DOI:
10.1371/journal.ppat.1011902

PMCID:
PMC10786383

PMID:
38166150

Journal Information

Full Title: PLoS Pathog

Abbreviation: PLoS Pathog

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Microbiology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
Transparency Indicators
Click on green indicators to view evidence text
Core Indicators
Evidence found in paper:

"biological replicates as indicated in the figure legend s1 data (xlsx) click here for additional data file s1 fig (a)the absolute cell number of immune organs were detected (b-e) cells were isolated from spleen (b) bone marrows (c) lymph nodes (d) and thymocytes (e) of wt mice or trim26-ko mice followed by flow cytometry analysis for the indicated immune cell populations (f-h) wild-type control mice or trim26-deficient mice were intravenous injected with live c albicans (2x10 5 cfu/100 ? xlsx) click here for additional data file s1"

Code Sharing
Evidence found in paper:

"The authors have declared that no competing interests exist."

Evidence found in paper:

"This work was supported by grants from the National Natural Science Foundation of China (82321002, 32230033, and 81930039 to CG.), grants from the National key research and development program (2021YFC2300603 to CG.), grants from Natural Science Foundation of Shandong Province (ZR2020MH165 to GZ.), and the grants from Cutting Edge Development Fund of Advanced Medical Research Institute awarded to YZ. The funders had no role in study design, data collection, and interpretation, or submitting the work for publication."

Protocol Registration
Open Access
Paper is freely available to read
Additional Indicators
Replication
Novelty Statement
Assessment Info

Tool: rtransparent

OST Version: N/A

Last Updated: Aug 05, 2025