Digital Clock and Recall is superior to the Mini-Mental State Examination for the detection of mild cognitive impairment and mild dementia.

"Declarations Ethics approval and consent to participateThe study was explained to participants verbally and through written informed consent that was approved by the local IRB of each site participating in the GAP consortium (see the Bio-Hermes study website [27] for a list of study sites). If, in the opinion of the site principal investigator, the participant did not have the capacity to sign the informed consent form, a legally authorized representative was used to grant consent on behalf of the participant. Consent for publicationThe manuscript does not contain any individual person’s data in any form. Competing interestsAPL is a co-founder and Chief Medical Officer of Linus Health and a co-founder of TI Solutions and declares ownership of shares or share options in the company. APL serves as a paid member of the scientific advisory boards for Neuroelectrics, Magstim Inc., TetraNeuron, Skin2Neuron, MedRhythms, and Hearts Radiant. DB is a co-founder and Chief Executive Officer of Linus Health and declares ownership of shares or share options in the company. JS is Chief Product Officer of Linus Health and declares ownership of shares or share options in the company. All other authors are employees of Linus Health and declare ownership of shares or share options in the company. Competing interests APL is a co-founder and Chief Medical Officer of Linus Health and a co-founder of TI Solutions and declares ownership of shares or share options in the company. APL serves as a paid member of the scientific advisory boards for Neuroelectrics, Magstim Inc., TetraNeuron, Skin2Neuron, MedRhythms, and Hearts Radiant. DB is a co-founder and Chief Executive Officer of Linus Health and declares ownership of shares or share options in the company. JS is Chief Product Officer of Linus Health and declares ownership of shares or share options in the company. All other authors are employees of Linus Health and declare ownership of shares or share options in the company."

"Funding This study was organized by the GAP Innovations, PBC via a grant from the Alzheimer’s Drug Discovery Foundation [64]."

"Trial registration ClinicalTrials.gov identifier NCT04733989."