Disruption of MAM integrity in mutant FUS oligodendroglial progenitors from hiPSCs.

Authors:
Zhu Y; Burg T; Neyrinck K; Vervliet T; Nami F and 13 more

Journal:
Acta Neuropathol

Publication Year: 2024

DOI:
10.1007/s00401-023-02666-x

PMCID:
PMC10764485

PMID:
38170217

Journal Information

Full Title: Acta Neuropathol

Abbreviation: Acta Neuropathol

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Neurology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"all fastq and supplementary files were uploaded to ncbi-geo under accession number gse239403. meanwhile the differential expression analysis for snrna-seq data was downloaded from supplementary dataset 3 of the corresponding study [ ]."

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Evidence found in paper:

"Declarations Conflict of interestThe authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. Ethics approvalThe ALS-patient-derived iPSCs used in this study were generated from patient-derived skin biopsies approved by the ethical committee of the University Hospital Leuven (S50354). Conflict of interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

Evidence found in paper:

"Funding YZ is funded by a PhD Fellowship of the China Scholarship Council (CSC) (201908440360). This project was supported by the University of Leuven C1 grants, C14-17-107 and C14/22/132; ALS-OL grant from the Thierry Latran Foundation; FWO-SBO-S001221N -ORGAN-ID to CV. LVDB is supported by the IDN/22/012, the Generet Award for Rare Diseases, the iBOF/23/02 and the ALS Liga (‘A Cure for ALS’). TB holds a senior post-doctoral grant of the FWO (12AIK24N). TV is a recipient of a senior post-doctoral grant of the FWO (12ZG121N). Work in the Bultynck team was supported by Research Council of the KU Leuven (C14/19/099 and AKUL/19/34). GB and PA are members of the FWO Scientific Research Network CaSign (W001422N)."

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Last Updated: Aug 05, 2025