Transcriptional profiling of human cartilage endplate cells identifies novel genes and cell clusters underlying degenerated and non-degenerated phenotypes.

Authors:
Kuchynsky K; Stevens P; Hite A; Xie W; Diop K and 5 more

Journal:
Arthritis Res Ther

Publication Year: 2024

DOI:
10.1186/s13075-023-03220-6

PMCID:
PMC10763221

PMID:
38173036

Journal Information

Full Title: Arthritis Res Ther

Abbreviation: Arthritis Res Ther

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Rheumatology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Core Indicators
Evidence found in paper:

"raw bulk (gse242040) and single-cell rna sequencing data (gse242443) are publicly available in the geo database. availability of data and materials all figures and tables referenced in this study are available within this published article or available as supplementary files. raw bulk (gse242040"

Code Sharing
Evidence found in paper:

"Declarations Ethics approval and consent to participateAll cadaveric human tissue samples were obtained through Ohio State University’s Cooperative Human Tissue Network and were obtained through an Institutional Review Board exemption as this research is classified as non-human subject research. Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."

Evidence found in paper:

"Funding Funding for this work was supported by the award UL1TR002733 from the National Center for Advancing Translational Sciences and NSF CAREER grant 2143123."

Protocol Registration
Open Access
Paper is freely available to read
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Tool: rtransparent

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Last Updated: Aug 05, 2025