Tumor microenvironment deconvolution identifies cell-type-independent aberrant DNA methylation and gene expression in prostate cancer.

"the dna methylation and rna-seq data used in this study were downloaded from the publicly available dataset gse183040 ( https://www ncbi nlm nih gov/geo/query/acc cgi?; acc=gse183040 ) and are available at the national center for biotechnology's gene expression omnibus repository.; availability of data and materials the dna methylation and rna-seq datasets analyzed during the current study are available under the national center for biotechnology's gene expression omnibus repository with the accession id--gse183040 https://www ncbi nlm nih gov/geo/query/acc cgi? availability of data and materials the dna methylation and rna-seq datasets analyzed during the current study are available under the national center for biotechnology's gene expression omnibus repository with the accession id--gse183040"

"Declarations Ethics approval and consent to participateThese are secondary analyses from a public anonymized dataset collected by the National Cancer Institute. All GEO datasets remove any personal or HIPAA-sensitive data. Consent for publicationNot applicable. Competing interestsBCC is an advisor for Guardant Health which had no role in this research. Competing interests BCC is an advisor for Guardant Health which had no role in this research."

"Funding B.C. Christensen is supported by the NIH grant numbers R01CA216265, R01CA253976, and P30GM149408. L.A. Salas is supported by the CDMRP/Department of Defense W81XWH-20-1-0778."