Antigen self-anchoring onto bacteriophage T5 capsid-like particles for vaccine design.

"the em map generated in this study has been deposited in the electron microscopy data bank under the number emd-14863."

"Competing interests P.B., E.V., N.D., L.L.C., and K.B. are named as inventors on a patent application filed by the CNRS and University Paris-Saclay based on the presented study (N° PCT/FR2020/051628, WO2021053309)."

"This work was supported by the Centre National de la Recherche Scientifique and the University Paris-Saclay. L.L.C., E.V., N.D., and C.V. received a fellowship from the French Ministère de l’Enseignement Supérieur et de la Recherche. L.L.C. received an additional fellowship from the Ligue Nationale contre le cancer. L.R.-C. received a fellowship “Becas Don Carlos Antonio Lopez” from the Paraguayan Ministry of Education. This work benefited from the Cryo-EM platform of I2BC, supported by the French Infrastructure for Integrated Structural Biology (FRISBI) [ANR-10-INSB-05-05] and member of IBISA. This work used the platforms of the Grenoble Instruct-ERIC center (ISBG; UAR3518 CNRS-CEA- UGA-EMBL) within the Grenoble Partnership for Structural Biology (PSB), supported by FRISBI (ANR- 10-INSB-05-02 & project ID 160 to P.B.) and GRAL, financed within the University Grenoble Alpes graduate school (Écoles Universitaires de Recherche) CBH-EUR-GS (ANR-17-EURE-0003). The electron microscope facility is supported by the Auvergne-Rhône-Alpes Region, the Fondation pour la Recherche Médicale (FRM), the fonds FEDER and the GIS-Infrastructures en Biologie Santé et Agronomie (IBiSA). IBS acknowledges integration into the Interdisciplinary Research Institute of Grenoble (IRIG, CEA). The authors are very grateful to the staff of the animal facility of Institut Gustave Roussy for technical help. We thank Héloise Croizet for her participation to ELISA experiments for the dose-response study, Loïc Levacher and Emmeline Huvelle for their contribution to CLP and pb10 chimera purification as well as Didier Poncet and Pierre Bobé for their critical reading of the manuscript."