A compendium of genetic regulatory effects across pig tissues.

Authors:
Teng J; Gao Y; Yin H; Bai Z; Liu S and 98 more

Journal:
Nat Genet

Publication Year: 2024

DOI:
10.1038/s41588-023-01585-7

PMCID:
PMC10786720

PMID:
38177344

Journal Information

Full Title: Nat Genet

Abbreviation: Nat Genet

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics, Medical

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
5/6
83.3% Transparent
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Evidence found in paper:

"code availability all the computational scripts and codes for rna-seq wgs wgbs single-cell rna-seq and hi-c dataset analyses as well as the respective quality control molecular phenotype normalization genotype imputation molqtl mapping functional enrichment colocalization smr and twas are available at the farmgtex github website ( https://github com/farmgtex/piggtex-pipeline-v0 10 6084/m9 figshare 24247771) 65 . code availability all the computational scripts and codes for rna-seq wgs wgbs single-cell rna-seq and hi-c dataset analyses as well as the respective quality control molecular phenotype normalization genotype imputation molqtl mapping functional enrichment colocalization smr and twas are available at the farmgtex github website ( https://github com/farmgtex/piggtex-pipeline-v0 10 6084/m9 figshare 24247771) 65 ."

Evidence found in paper:

"code availability all the computational scripts and codes for rna-seq wgs wgbs single-cell rna-seq and hi-c dataset analyses as well as the respective quality control molecular phenotype normalization genotype imputation molqtl mapping functional enrichment colocalization smr and twas are available at the farmgtex github website ( https://github com/farmgtex/piggtex-pipeline-v0 10 6084/m9 figshare 24247771) 65 ."

Evidence found in paper:

"Competing interests The authors declare no competing interests."

Evidence found in paper:

"Zhe Zhang (SCAU) acknowledges funding from the National Natural Science Foundation of China (32022078), the National Key R&D Program of China (2022YFF1000900) and the Local Innovative and Research Teams Project of Guangdong Province (2019BT02N630), and support from National Supercomputer Center in Guangzhou, China. Y.C., Zhe Zhang (SCAU), Jiaqi Li, X. Liu, X.D. and S.Z. acknowledge funding from the China Agriculture Research System (CARS-35). L. Fang acknowledges funding from HDR-UK under award HDR-9004 and the European Union’s Horizon 2020 research and innovation program under the Marie Skłodowska-Curie grant agreement 801215. G.E.L. was supported by United States Department of Agriculture (USDA) National Institute of Food and Agriculture (NIFA) AFRI under grant numbers 2019-67015-29321 and 2021-67015-33409 and the appropriated project 8042-31000-112-00-D, ‘Accelerating Genetic Improvement of Ruminants Through Enhanced Genome Assembly, Annotation, and Selection’ of the USDA Agricultural Research Service (ARS). This research used resources provided by the SCINet project of the USDA ARS under project 0500-00093-001-00-D. Mention of trade names or commercial products in this article is solely for the purpose of providing specific information and does not imply recommendation or endorsement by the USDA. The USDA is an equal opportunity provider and employer. A.T. acknowledges funding from the BBSRC through program grants BBS/E/D/10002070 and BBS/E/D/30002275, MRC research grant MR/P015514/1 and HDR-UK award HDR-9004. P.N. and C.H. were supported by the Medical Research Council, UK (grant MC_UU_00007/10). O.C.-X. was supported by MR/R025851/1. M.B. and D.C.-P. belonged to a Consolidated Research Group AGAUR, ref. 2017SGR-1719, and D.C.-P. was supported by the GENE-SWitCH project (https://www.gene-switch.eu), which is funded by the European Union’s Horizon 2020 research and innovation program under the grant agreement 817998. R.X. was supported by the Australian Research Council’s Discovery Projects (DP200100499). L.M. was supported in part by AFRI under grants 2020-67015-31398 and 2021-67015-33409 from the USDA NIFA. B.N.K. and G.A.R. were supported by appropriated project 3040-31000-099-000-D, ‘Identifying Genomic Solutions to Improve Efficiency of Swine Production’ of the ARS of the USDA. A.K.L.P. and W.T.O. were supported by appropriated project 3040-31000-102-000-D, ‘Optimizing Nutrient Management and Efficiency of Beef Cattle and Swine’ of the ARS of the USDA. Z.P., D.G. and H. Zhou, and computational resource were supported in part by Agriculture and Food Research Initiative Competitive grants 2018-67015-27501 and 2015-67015-22940. All the funders had no role in study design, data collection and analysis and decision to publish or prepare the manuscript."

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Last Updated: Aug 05, 2025