Elevated HIV Viral Load is Associated with Higher Recombination Rate In Vivo.

"the single genome sequencing data from caskey et al (2017) can be downloaded from genbank (accession numbers ky323724 - ky324834 ) while the viral load measurements from the study are listed in supplementary table 3 of caskey et al (2017) ."

"all code to reproduce these analyses can be found at https://github com/federlab/hiv-recombination ."

"The authors would like to thank Richard Neher for assistance accessing data from Participant 6, in addition to Kelley Harris, Benjamin Kerr, Daniel Reeves, Lillian Cohn, Elena Giorgi, Nandita Garud, Pleuni Pennings, the Cohn lab at Fred Hutchinson Cancer Center and the Feder lab at the University of Washington for useful discussions on this project and feedback on the manuscript. The authors would like to especially thank Fabio Zanini, two anonymous reviewers, and the editor for providing valuable feedback on this work. E.V.R. was supported by the UW Statistical Genetics Training Grant (T32GM081062). This independent research was supported by the Gilead Sciences Research Scholars Program in HIV."