Long-Term Overall Survival After Selective Internal Radiation Therapy for Locally Advanced Hepatocellular Carcinomas: Updated Analysis of DOSISPHERE-01 Trial.

"DISCLOSURE Etienne Garin reports receiving a grant, personal fees, and nonfinancial support from Boston Scientific during the conduct of the study. Lambros Tselikas reports personal fees from Boston Scientific, Sirtex, and GE Healthcare; grants from Terumo and the Bristol Myers Squibb Foundation; and nonfinancial support from GE Healthcare during the conduct of the study. Boris Guiu reports personal fees from Boston Scientific during the conduct of the study. Julien Edeline reports receiving a grant from Boston Scientific during the conduct of the study; personal fees from Boston Scientific, Bayer, Roche, Eisai, Merck Sharpe & Dohme, AstraZeneca, and Ipsen; grants and personal fees from Bristol Myers Squibb; and nonfinancial support from Amgen outside the submitted work. Thierry de Baere reports grants from Terumo and personal fees from Guerbet and Terumo during the conduct of the study. Antoine Hollebecque reports nonfinancial support from Servier, Incyte, and Lilly and personal fees from Amgen, Eisai, and Gritstone Oncology outside the submitted work. Helen Regnault reports personal fees from Boston Scientific outside the submitted work. Xavier Palard, Boris Campillo-Gimenez, and Yan Rolland report receiving a grant from Boston Scientific during the conduct of the study. No other potential conflict of interest relevant to this article was reported."

"All patients provided written informed consent before undergoing study-specific procedures. The study was performed in accordance with the Declaration of Helsinki principles. The study protocol was approved by the ethics committee of the University Hospital La Cavalle Blanche (IRB-ID approval 2015-A00894-45) and registered on ClinicalTrials.gov (NCT02582034)."