Sulforaphane effectively inhibits HBV by altering Treg/Th17 immune balance and the MIF-macrophages polarizing axis in vitro and in vivo.

"data availability data will be made available on request. acknowledgments this work was supported by the [grant number 81570 541] the min-sheng project of chongqing science and technology [grant number cstc2017shmsa 130097"

"Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper."

"This work was supported by the 10.13039/501100001809National Natural Science Foundation of China [grant number 81570 541], the Min-Sheng Project of Chongqing Science and Technology [grant number cstc2017shmsA 130097], the Chongqing Postgraduate Innovation Project in Scientific Research [grant number CYS 21243], and the 10.13039/501100001809National Natural Science Foundation of China [grant number 82172619]."