Long-term inhibition of ODC1 in APP/PS1 mice rescues amyloid pathology and switches astrocytes from a reactive to active state.

Authors:
Bhalla M; Lee CJ.

Journal:
Mol Brain

Publication Year: 2024

DOI:
10.1186/s13041-024-01076-8

PMCID:
PMC10785549

PMID:
38216963

Journal Information

Full Title: Mol Brain

Abbreviation: Mol Brain

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Molecular Biology

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
4/6
66.7% Transparent
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Evidence found in paper:

"funding this work was supported by the institute for basic science (ibs) center for cognition and sociality (ibs-r001-d2) to c j l availability of data and materials the ngs dataset supporting the conclusions of this article is available in the ncbi geo repository https://www ncbi nlm nih gov/geo ; geo: gse185916. availability of data and materials the ngs dataset supporting the conclusions of this article is available in the ncbi geo repository https://www ncbi nlm nih gov/geo ; geo: gse185916"

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Evidence found in paper:

"Declarations Ethics approval and consent to participateNot applicable. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

Evidence found in paper:

"Funding This work was supported by the Institute for Basic Science (IBS), Center for Cognition and Sociality (IBS-R001-D2) to C.J.L."

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Open Access
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Last Updated: Aug 05, 2025