Efficacy, safety and genomic analysis of SCT200, an anti-EGFR monoclonal antibody, in patients with fluorouracil, irinotecan and oxaliplatin refractory RAS and BRAF wild-type metastatic colorectal cancer: a phase Ⅱ study.

Authors:
Yang L; Zhang W; Fan N; Cao P; Cheng Y and 22 more

Journal:
EBioMedicine

Publication Year: 2024

DOI:
10.1016/j.ebiom.2024.104966

PMCID:
PMC10826138

PMID:
38217945

Journal Information

Full Title: EBioMedicine

Abbreviation: EBioMedicine

Country: Unknown

Publisher: Unknown

Language: N/A

Publication Details

Subject Category: Genetics, Medical

Available in Europe PMC: Yes

Available in PMC: Yes

PDF Available: No

Transparency Score
3/6
50.0% Transparent
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Evidence found in paper:

"Declaration of interests Liangzhi Xie, Wenlin Gai, and Yan Wang are employees of Sinocelltech Ltd., Beijing, China. Peng Meng is employee of Burning Rock Biotech, Shanghai, China. The other authors declare that there is no conflict of interests regarding the publication of this article."

Funding Disclosure
Evidence found in paper:

"The study protocols were approved by the ethics committee of all the participating hospitals in accordance with the Declaration of Helsinki and its amendments. Written informed consent of every patient was obtained before enrollment. The clinical trial registration number was NCT03405272."

Open Access
Paper is freely available to read
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Last Updated: Aug 05, 2025