ATG7/GAPLINC/IRF3 axis plays a critical role in regulating pathogenesis of influenza A virus.

"the rna-seq data have been deposited in geo public database under the accession number gse211357.; the rna-seq data have been deposited in geo public database under the accession number gse211357.; the rna-seq data have been deposited in geo public database under the accession number gse211357. data availability all relevant data are within the manuscript figures and supporting information files. the rna-seq data have been deposited in geo public database under the accession number gse211357"

"The authors have declared that no competing interests exist."

"This work was supported by National Natural Science Foundation of China (32030110 to JLC, U23A20235 to JLC) and National Key Research and Development Program of China (2021YFD1800205 to JLC).The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript."