Histidine transport is essential for the growth of Staphylococcus aureus at low pH.

"plos publication stage vor-update-to-uncorrected-proof publication update 2024-01-26 data availability the illumina sequence reads for the tn-seq experiment using library a were deposited in the short read archive (sra) at the national center for biotechnology information (ncbi) under bioproject id prjna998095 and run number srr25408001.; the illumina sequence reads for the tn-seq experiment using library b were deposited as part of a previous study in the short read archive (sra) under bioproject id prjna544248 and accession number srx5883253.; illumina sequence reads for the suppressor strains were deposited into the european nucleotide archive (ena) under project number prjeb62451.; data availability the illumina sequence reads for the tn-seq experiment using library a were deposited in the short read archive (sra) at the national center for biotechnology information (ncbi) under bioproject id prjna998095 and run number srr25408001.; the illumina sequence reads for the tn-seq experiment using library b were deposited as part of a previous study in the short read archive (sra) under bioproject id prjna544248 and accession number srx5883253.; illumina sequence reads for the suppressor strains were deposited into the european nucleotide archive (ena) under project number prjeb62451.; the illumina sequence reads for the tn-seq experiment using library a were deposited in the short read archive (sra) at the national center for biotechnology information (ncbi) under bioproject id prjna998095 and run number srr25408001.; the illumina sequence reads for the tn-seq experiment using library b were deposited as part of a previous study in the short read archive (sra) under bioproject id prjna544248 and run number srx5883253 [ ].; for genome sequence analysis a previously described protocol using the clc workbench genomics software (qiagen) was used [ ] and the reads were mapped to a custom s aureus usa300 lac* reference genome generated in a previous study and for which the illumina reads have been deposited into the european nucleotide archive (ena) under project number prjeb14759 [ ].; illumina sequence reads for the suppressor strains were deposited into the european nucleotide archive (ena) under project number prjeb62451. the raw data for all graphs are provided in the s1 data file.; the average od 600 readings from three experiments were plotted (docx) click here for additional data file s1 data (xlsx) click here for additional data file. s1 table (xlsx"

"The authors have declared that no competing interests exist."

"This work was supported by the Wellcome trust (https://wellcome.org/) grant 210671/Z/18/Z/WT to A.G. The funder did not play any role in the study design, data collection and analysis, preparation of the manuscript or decision to publish."