Syphilis epidemic among men who have sex with men: A global systematic review and meta-analysis of prevalence, incidence, and associated factors.

"Disclosure of interest: The authors completed the ICMJE Disclosure of Interest Form (available upon request from the corresponding author) and disclose no relevant interests."

"Funding: This work was supported by the National Natural Science Foundation of China [grant number 72204214]. The funders of the study had no role in study design, data collection, data analysis, data interpretation, writing of the report, or the decision to submit the study for publication."

"We conducted this systematic review and meta-analysis per the PRISMA guidelines and registered the protocol in PROSPERO (CRD42023422218). We comprehensively searched PubMed, Embase, and the Cochrane Library using a combination of MeSH and free text terms between 1 January 2012 and 31 December 2022. We also hand-searched HIV/STI-related conference databases (e.g. the International Acquired Immunodeficiency Syndrome (AIDS) Conference, the STI&HIV World Congress, the European Conference on Sexually Transmitted Infections) (Text S1 in the ). Articles and citations were managed in EndNote X9 (Clarivate Analytics, Philadelphia, USA) Registration: PROSPERO: CRD42023422218."