Performance of a seed amplification assay for misfolded alpha-synuclein in cerebrospinal fluid and brain tissue in relation to Lewy body disease stage and pathology burden.

"Declarations Conflict of interestThe authors declare there are no competing interests. Ethical approvalThe study was conducted according to the revised Declaration of Helsinki and Good Clinical Practice guidelines and approved by the local ethics committee (approval number AVEC:18025, 113/2018/OSS/AUSLBO). Informed consentWritten informed consent was given by study participants or the next of kin. Consent for publicationNot applicable. Conflict of interest The authors declare there are no competing interests."

"Funding Open access funding provided by Alma Mater Studiorum - Università di Bologna within the CRUI-CARE Agreement. The study was supported by the grant Ricerca Finalizzata-2021–12374386 and “Ricerca Corrente” funded by the Ministero della Salute, and the #NextGenerationEU (NGEU), funded by the Ministry of University and Research (MUR), National Recovery and Resilience Plan (NRRP), project MNESYS (PE0000006)."