The genomic alterations in glioblastoma influence the levels of CSF metabolites.

"Declarations Ethics approval and consent to participateSample collection and processing and data collection and use were performed in accordance with local ethics regulations and approvals as well as the 1964 Helsinki declaration and its later amendments. All procedures were performed in accordance with local institutional review board guidelines. Patients consented to the use of their samples in this research project. Consent for publicationNot applicable. Competing interestsThe authors declare that they have no competing interests. Competing interests The authors declare that they have no competing interests."

"Funding Research reported in this publication was supported by the National Cancer Institute of the National Institutes of Health under award number K08CA241651 (LYB). CBP is a McNair Scholar supported by the McNair Medical Institute at The Robert and Janice McNair Foundation. This work was partly supported by the generous philanthropic contributions to The University of Texas MD Anderson Cancer Center Glioblastoma Moon Shots Program™. The metabolomics core was supported by CPRIT Core Facility Support Award RP210227 (“Proteomic and Metabolomic Core Facility”), NCI Cancer Center Support Grant P30CA125123, NIH/NCI grant R01CA282282, NIH/NCI grant R01CA216426, and intramural funds from the Dan L. Duncan Cancer Center."