Histone deacetylase inhibitors VPA and WT161 ameliorate the pathological features and cognitive impairments of the APP/PS1 Alzheimer's disease mouse model by regulating the expression of APP secretases.
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Full Title: Alzheimers Res Ther
Abbreviation: Alzheimers Res Ther
Country: Unknown
Publisher: Unknown
Language: N/A
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"Declarations Ethics approval and consent to participateAll animal experiments in the present research were performed according to the recommendations of the National Institute of Health Guide for the Care and Use of Laboratory Animals. The methods were approved by the Animal Ethics Committee of Tianjin Medical University (TMUaMEC 2022020). Consent for publicationNot applicable. Competing interestsThe authors declare no competing interests. Competing interests The authors declare no competing interests."
"Funding This study was supported by The National Natural Science Foundation of China (32170649, 92046014, 81801323), Beijing-Tianjin-Hebei Jointed Research Program (19JCZDJC64700) and National Key R&D Program of China (2017YFC1001900)."
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Last Updated: Aug 05, 2025