A systematic literature review of the human papillomavirus prevalence in locally and regionally advanced and recurrent/metastatic head and neck cancers through the last decade: The "ALARM" study.

"additionally hpv prevalence in la and rm opc geographic distribution of hpv prevalence and level of homogeneity between hpv testing methodologies were explored 2 this slr was conducted and outcomes were reported in accordance with prisma guidelines (see data s1 ).; the detailed search strategy including search strings and resulting number of hits is provided in data s2 .; data s1: supporting information."

"CONFLICT OF INTEREST STATEMENT Sofia Agelaki is a member of the executive board of the Hellenic Society of Medical Oncology, has served as an investigator in clinical studies for MSD Greece, has received consulting fees for participating in Expert Input Forums for MSD Greece, and has received lecture honoraria by MSD Greece. Ioannis Boukovinas, former president of the Hellenic Society of Medical Oncology, has served as an investigator in clinical studies for MSD Greece, has received consulting fees for participating in Advisory Boards for MSD Greece, has received lecture honoraria by MSD Greece, and has received support for attending international congress from MSD Greece. Ilias Athanasiadis has served as an investigator in clinical studies for MSD Greece, has received consulting fees for participating in Advisory Boards for MSD Greece, has received lecture honoraria by MSD Greece, and has received support for attending international congress from MSD Greece. Georgios Trimis, Ioannis Dimitriadis, Lazaros Poughias, and Charalampos Athanasopoulos are employees of MSD Greece and own stock in Merck & Co., Inc., Rahway, NJ, US. Edith Morais is an employee of MSD France and owns stock in Merck & Co., Inc., Rahway, NJ, US. Sabale Ugne is an employee of MSD Sweden and owns stock in Merck & Co., Inc., Rahway, NJ, US. Goran Bencina is an employee of MSD Spain and owns stock in Merck & Co., Inc., Rahway, NJ, US."

"FUNDING INFORMATION This work was funded by Merck Sharp & Dohme LLC, a subsidiary of Merck & Co, Inc., Rahway, NJ, USA."

"This SLR was conducted and outcomes were reported in accordance with PRISMA guidelines (see Data ). The study protocol was registered with PROSPERO, the international prospective register of systematic reviews (registration number: CRD42021256876) and is publicly available."