A bioactive composite hydrogel dressing that promotes healing of both acute and chronic diabetic skin wounds.

"Declaration of competing interest The authors declare no conflict of interest. Conflicts of interest All authors declare no conflicts of interest."

"This work was supported by National High Level Hospital Clinical Research Funding, (2023-NHLHCRF-YS-01), 10.13039/501100012173Elite Medical Professionals Project of China-Japan Friendship Hospital (ZRJY2023-GG06), the 10.13039/501100002858China Postdoctoral Science Foundation (Certificate Number: 2023M733986 and 2023T160741), Cross-sectional project of China-Japan Friendship Hospital(Certificate Number:2023-HX-JC-10), International Association of Chinese Nephrologists Research Grant(No. IACNRG-01) and Beijing Hospitals Authority Clinical medicine Development of special funding support(Certificate Number: ZLRK202308). Shunlai Shang: Writing – original draft, Supervision, Software, Project administration, Investigation, Funding acquisition, Data curation, Conceptualization. Kaiting Zhuang: Supervision, Software, Project administration, Investigation, Data curation. Jianwen Chen: Validation, Software, Investigation, Data curation. Ming Zhang: Supervision, Investigation, Funding acquisition, Conceptualization. Shimin Jiang: Writing – original draft, Software, Resources, Project administration, Formal analysis, Conceptualization. Wenge Li: Writing – review & editing, Visualization, Software, Project administration, Investigation, Funding acquisition, Data curation, Conceptualization."